Composite
Part:BBa_K3110052:Design
Designed by: Amartya Pal Group: iGEM19_IISER_Tirupati (2019-10-16)
lldRO1-J23117-lldRO2-Medium RBS-YebF IL12
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12INCOMPATIBLE WITH RFC[12]Illegal NheI site found at 78
Illegal NheI site found at 101 - 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
Here we have put a lldRO1-J23117-lldRO2 along with B0032 (which is a medium strength RBS) and downstream to it, we have attached YebF-IL12 and FLAG-tag.
Source
YebF-IL12-FLAG tag was synthesized by Twist Bioscience. lldRO1-J23117-lldRO2 + B0032 and B0015 were obtained as gBlocks from IDT and these 3 parts were joined together using SOEing (Spliced Overlap Extension) PCR.